Mouse Anti-Rat KCC2 Monoclonal Antibody (CBP3998)
[CAT#: NAB20121006LS]
Anti-KCC2 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Rat
- Applications:
- WB; IHC-P
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Potassium-chloride cotransporter member 5 (also known as KCC2 and SCL12A5) is responsible for establishing the chloride ion gradient in neurons through the maintenance of low intracellular chloride concentrations. Mediates synaptic inhibition, protects against excitotoxicity and modulates plasticity.
Immunogen
This monoclonal antibody was raised against a fusion protein corresponding to amino acids 932-1043 (intracellular carboxyl terminus) of rat KCC2b.
Species Reactivity
Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a, κ
Clone Number
CBP3998
Applications
WB; IHC-P
Application Notes
WB (10.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
KCC2
Official Name
SLC12A5
Full Name
Potassium-chloride transporter member 5
Alternative Names
SLC12A5; KCC2; Chloride potassium symporter 5; EIEE34; EIG14; hKCC2; solute carrier family 12 member 5
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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