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Creative Biolabs

Mouse Anti-Inhibin α Monoclonal Antibody (CBP4265)

[CAT#: NAB210135LS]

Anti-Inhibin α Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB

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Product Overview

Description

Inhibin α (INHA) interacts with INHBA or INHBB to form a dimeric inhibitor for Follicle-stimulating hormone secretion. Due to its role in regulating gonadal stromal cell proliferation, it has been implicated in cancer research, and has been used as a marker of ovarian cancer. Clinically, INHA levels is also part of the prenatal quad screen during second trimester as preliminary indicator of Down syndrome.

Immunogen

Recombinant Inhibin A (INHA) expressed in E. coli.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP4265

Applications

WB

Application Notes

WB (0.5-2.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Inhibin Beta B

Official Name

INHBB

Full Name

Inhibin, beta B

Alternative Names

INHBB; inhibin beta B subunit; inhibin subunit beta B

Gene ID

3625(Human); 16324(Mouse); 25196(Rat)

Uniprot ID

P09529(Human); Q04999(Mouse); P17491(Rat)
References

1. Robertson DM, et al. 2007. Cancer Letters. 249(1):14
2. Kommoss F, et al. 2019. Pathologe. 40(1):61
3. Lee Y, et al. 2019. Obes Surg. 29(1):334
Publications

Publications (0)

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