Product Overview

Description

It is a mouse monoclonal to LRRK2.

Expression Host

Mammalian cells

Immunogen

Partial recombinant protein

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP4409

Applications

IHC; WB

Relevant Diseases

Parkinson's Disease

Research Areas

Neurogenesis; Neural Signal Transduction

Conjugation

HRP

Product Properties

Form

Liquid

Formulation

PBS with 0.09% (W/V) sodium azide.

Preservatives

Yes

Purification

Protein G Affinity Chromatography

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

LRRK2

Official Name

LRRK2

Full Name

Leucine-rich repeat kinase 2

Alternative Names

LRRK2; AURA17; DARDARIN; PARK8; RIPK7; ROCO2; leucine-rich repeat kinase 2; leucine rich repeat kinase 2

Gene ID

120892(Human); 66725(Mouse); 300160(Rat)

Uniprot ID

Q5S007(Human); Q5S006(Mouse)

References

1. Lee, J. H., Han, J. H., Kim, H., Park, S. M., Joe, E. H., & Jou, I. (2019). Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes. Acta neuropathologica communications, 7(1), 1-19.

Publications