NoGeneST™ Anti-MeCP2 Aptamer, aMeCP2 aptamer

Name: NoGeneST™ Anti-MeCP2 Aptamer, aMeCP2 aptamer
SKU: NRYF-0625-HZ111
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ111]

Aptamer designed to specifically recognize Methyl-CpG-Binding Protein 2, a key epigenetic reader implicated in Rett syndrome.

Target:: MeCP2

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Product Overview

Relevant Diseases

Autism Spectrum Disorder

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

MeCP2

Full Name

Methyl-CpG-Binding Protein 2

Gene ID

4204

Uniprot ID

P51608

Target Overview

Methyl-CpG-binding protein 2 (MeCP2) is a nuclear protein that acts as a critical reader and interpreter of the epigenome. It specifically binds to methylated DNA at CpG sites, which are regions where a cytosine nucleotide is followed by a guanine nucleotide. Upon binding, MeCP2 recruits other protein complexes to modify chromatin structure and repress gene transcription. This function is essential for the proper maturation and maintenance of neurons. Mutations in the MECP2 gene are the primary cause of Rett syndrome, a severe X-linked neurodevelopmental disorder that predominantly affects females.

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