NoGeneST™ Anti-Neuroligin Aptamer, aNeuroligin aptamer

Name: NoGeneST™ Anti-Neuroligin Aptamer, aNeuroligin aptamer
SKU: NRYF-0625-HZ114
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ114]

Aptamer designed to specifically recognize Neuroligin, a family of postsynaptic cell adhesion molecules implicated in autism and synaptic function.

Target:: Neuroligin

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Product Overview

Relevant Diseases

Autism Spectrum Disorder

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

Neuroligin

Full Name

Neuroligin-1

Alternative Names

NLGN1

Gene ID

22941

Uniprot ID

Q8N2Q7

Target Overview

Neuroligins are a family of postsynaptic cell adhesion molecules that are fundamental to the development and function of synapses in the brain. They act as binding partners for presynaptic Neurexins, forming a trans-synaptic bridge that is critical for recruiting neurotransmitter receptors and other essential synaptic components. This Neurexin-Neuroligin complex helps organize and stabilize synapses, with different Neuroligins localizing to either excitatory (e.g., Neuroligin-1) or inhibitory (e.g., Neuroligin-2) synapses. Genetic mutations affecting Neuroligin function are strongly associated with neurodevelopmental disorders, particularly Autism Spectrum Disorder (ASD).

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