NoGeneST™ BACE1-ASO, Antisense Oligonucleotide

Name: NoGeneST™ BACE1-ASO, Antisense Oligonucleotide
SKU: NRYF-0625-XY70
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-XY70]

Target:: BACE1

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Product Overview

Description

BACE1-ASO is designed to target the mRNA of BACE1, preventing the enzyme from being produced and potentially inhibiting amyloid-beta production.

Species

Human

Applications

Inhibits BACE1 expression to reduce Aβ peptide generation in AD research. Facilitates studies on BACE1-mediated synaptic dysfunction, neuroinflammation, and blood-brain barrier integrity. Optimized for preclinical models evaluating BACE1-targeted therapies, including in vivo assessments of cognitive function in AD mice.

Relevant Diseases

Alzheimer disease

Properties

Appearance

Solid

Shipping

Room temperature

Storage

Store at -20°C, sealed and away from moisture.
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).

Research Use Only

For research use only.

Target Details

Target

BACE1

Official Name

BACE1

Full Name

Beta-Secretase 1

Alternative Names

Beta-Secretase 1; Membrane-Associated Aspartic Protease 2; Beta-Site APP Cleaving Enzyme 1; Beta-Site APP-Cleaving Enzyme; Aspartyl Protease 2; EC 3.4.23.46; Memapsin-2; Asp 2; BACE; ASP2

Publications