Product
Human HEK293/EP1 Stable Cell Line
[CAT#: NCL20120116CR]
EP1 Prostanoid Receptor Stable Cell Line
- Species:
- Human
- Applications:
- GPCR Screening
- Cell Types:
- HEK293; GPCR Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
Prostaglandin E2 receptor, EP1 subtype (EP1/PTGER1) is a receptor for prostaglandin E2 (PGE2). The members of the EP receptor family, EP1, EP2, EP3, and EP4, elicit their actions by altering cyclic adenosine monophosphate (cAMP) or intracellular calcium concentrations. EP1 activates phospholipase C and phosphatidylinositol turnover and stimulates the release of intracellular calcium via a Gi/Gq-coupled mechanism. EP2 and EP4 both signal through a Gs-coupled mechanism that stimulates adenylyl cyclase and increases intracellular levels of cAMP.
Cell Types
HEK293; GPCR Cell
Applications
GPCR Screening
Research Areas
GPCR; Neural Cell
Species
Human
Properties
Size
>1x10^6 Cells
Form
Frozen cells
Culture Medium
DMEM, 10% FBS, 200 μg/ml Zeocin, 250 μg/ml G418
Freeze Medium
45% culture medium, 45% FBS, 10% DMSO
Receptor
EP1/PTGER1
Family
Prostanoid receptor
Strain
EP1 Cell Line
Cell Purity
>95%
Shipping
Dry ice
Storage
Liquid nitrogen immediately upon delivery
Handling Advice
Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
repeated exposure.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Warnings
Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.
Target Details
Target
EP1
Official Name
EP1
Alternative Names
EP1 receptor; prostaglandin E; EP1; prostaglandin E receptor 1 (subtype EP1); 42kD; EP1 prostanoid receptor; PGE receptor EP1 subtype; PGE receptor; EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1; prostaglandin E receptor 1 (subtype EP1); prostaglandin E receptor EP1 subtype; prostaglandin E2 receptor EP1 subtype; prostanoid EP1 receptor; Ptgerep1; 42kDa
References
1. Montagna, E., Crux, S., Luckner, M., Herber, J., Colombo, A. V., Marinković, P.,.. & Sgobio, C. (2019). In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria. Glia, 67(5), 985-998. 2. Xu, Y., Wu, X., Wang, S., Yang, C., Li, Y., & Cao, Y. (2019). Hydroxyapatite Nanoparticle-Crosslinked Peptide Hydrogels for Three-Dimensional Culture and Differentiation of MC3T3-E1 Osteoblasts. Journal of biomedical nanotechnology, 15(12), 2351-2362. 3. Lan, J., Rollins, J. A., Zang, X., Wu, D., Zou, L., Wang, Z.,.. & Chen, D. (2019). Translational regulation of non-autonomous mitochondrial stress response promotes longevity. Cell reports, 28(4), 1050-1062.
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
