Mouse Cementoblasts, Immortalized

[CAT#: NCL-2108P138]

Species:: Mouse

Applications:: Cell Culture

Cell Types:: Tooth-related Cells

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Product Overview

Description

Cementum is the mineralized tissue on the surface of the tooth root, which has many characteristics in common with bone and other mineralized tissues. It plays a role in repair activities, tissue regeneration, and is responsible for maintaining healthy periodontal tissue. Immortalized Mouse Cementoblasts are immortalized using mouse SV40 large T antigen and retain the phenotypic characteristics of primary cells, such as parathyroid hormone 1 receptor (PTH-1), non-collagen (BSP, OC, OPN) and type I Collagen expression. In addition, this cell line has been shown to respond to the presence of parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP), and to stimulate the formation of mineral nodules.

Cell Types

Tooth-related Cells

Applications

Cell Culture

Species

Mouse

Properties

Size

>1x10^6 Cells

Growth Pattern

Adherent

Morphology

Polygon

Immortalization Method

Continuous passage and transduction with recombinant lentivirus carrying SV40 large T antigen

Freeze Medium

90%FBS+10%DMSO

Tissue Source

Oral

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

• Each vial contains ≥ 1X10^6 viable cells.
• Cells are tested by PCR and are negative for Hepatitis A, B, C, HPV, Herpes and HIV-1 & 2 viruses.
• Cells are negative for mycoplasma contamination.

Publications