Creative Biolabs

iNeu™Mito™ Mitochondrial Biosensor Assay using Human Astrocytes

[CAT#: NCL-2103-P60]

Cell Types:

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Product Overview


iNeuMito™ cells contain mitochondrial biosensors in astrocytes derived from human iPS. The destruction of mitochondrial function in human astrocytes is related to Alzheimer's disease and ischemia. iNeu's biosensor can respond to changes in mitochondrial calcium and report an increase or decrease in calcium content in the 605nm-625nm fluorescence range (excitation/emission). These sensors have an excellent signal-to-noise ratio and can operate in the range of seconds to minutes. This tool provides an effective method for detecting changes in mitochondrial organelles and enables high-throughput screening methods for drug discovery and toxicology screening.

Cell Types


Application Notes


Neurotoxicity testing for reporting mitochondrial calcium fluctuations
Phenotypic Screening (e.g., mitochondrial toxicity)
Chemical compound or small molecules testing
Research and Drug Development for human mitochondrial diseases, myelin disorders and neurodegnerative disorders
Studying astrocyte differentiation and function, and calcium-mediated signal transduction pathways




~0.6x10^6 cells per 1ml of freezing medium (vial)

Growth Pattern


Cell Purity


Cell Viability


Mycoplasma Testing

The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.

Sterility Testing

Sterility testing was performed in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Genetic Stability Testing

Cell genetic stability study was perfomed under ICH guidelines. We provide guidance on the appropriate testing program upon your requirements.


Dry ice


Liquid Nitrogen

Handling Advice

Frozen cells: Upon receipt, frozen ampoules should be transferred directly to gaseous phase liquid nitrogen without delay, unless they are to be used straight away.

Growing cells: Growing cell cultures should be checked on receipt using an inverted microscope. Immediately check the cell density upon arrival for any obvious defects. If the cell density is too high (more than 80% confluent) subculture the cells (harvest and reseed) immediately.

For detailed instructions on the thawing procedure of frozen cells and the culture of adherent or suspended cells, please feel free to contact us by email or phone.

Research Use Only

For research use only, not for diagnostic or therapeutic use.


Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents. It is recommended to use cells within ten generations.

Quality Control

Sterility, Safety, (BioSafety Level 2), HIV/viruses, bacteria, fungi: negative; Cell viability post-thawing (>90%)
Donor Information

Donor Health


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For Research Use Only. Not For Clinical Use.
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