Product Overview

Description

It is a mouse monoclonal to LRRK2.

Expression Host

Mammalian cells

Immunogen

Recombinant protein

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP4404

Applications

WB; ELISA

Relevant Diseases

Parkinson's Disease

Research Areas

Neurogenesis; Neural Signal Transduction

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC

Product Properties

Form

Liquid

Formulation

PBS with 0.09% (W/V) sodium azide.

Preservatives

Yes

Concentration

1 mg/mL

Purification

Protein G Purified

Purity

>95%, as determined by SDS-PAGE

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

LRRK2

Official Name

LRRK2

Full Name

Leucine-rich repeat kinase 2

Alternative Names

LRRK2; AURA17; DARDARIN; PARK8; RIPK7; ROCO2; leucine-rich repeat kinase 2; leucine rich repeat kinase 2

Gene ID

120892(Human); 66725(Mouse); 300160(Rat)

Uniprot ID

Q5S007(Human); Q5S006(Mouse)

References

1. Chuang, C. L., Lu, Y. N., Wang, H. C., & Chang, H. Y. (2014). Genetic dissection reveals that Akt is the critical kinase downstream of LRRK2 to phosphorylate and inhibit FOXO1, and promotes neuron survival. Human molecular genetics, 23(21), 5649-5658.

Publications