Mouse Anti-Human Arginase 1 Monoclonal Antibody (CBP3921)
[CAT#: NAB2012534LS]
Anti-Arginase 1 Monoclonal Antibody [PE]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FC
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Lot Number
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Lot Number
SPECIFIC INQUIRY
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Description
ARG1 (Arginase 1) is a marker of M2 anti-inflammatory macrophage subgroup, which can hydrolyze L-arginine into urea and ornithine, and it can be used in wound healing, antiviral immune response and atherosclerosis Play an important role in A genetic defect in this enzyme leads to argininemia, an autosomal recessive genetic disease characterized by hyperammonemia. Recent studies have shown that intracellular pathogens induce the expression of ARG1 in mouse macrophages through the Toll-like receptor (TLR) pathway. The absence of this enzyme in macrophages facilitates the survival of the host. Other studies have shown that ARG1 also plays a role in T cell responses, and selective antagonists of ARG1 may prove beneficial in fighting diseases that improperly suppress T cell responses
Immunogen
Full length recombinant protein expressed in E.coli.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP3921
Applications
FC
Application Notes
FCM (5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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