NoGeneST™ Anti-MBP Aptamer, aMBP aptamer

Name: NoGeneST™ Anti-MBP Aptamer, aMBP aptamer
SKU: NRYF-0625-HZ107
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ107]

Aptamer designed to specifically recognize Myelin Basic Protein, a fundamental component of the myelin sheath and an autoantigen in Multiple Sclerosis.

Target:: MBP

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Product Overview

Relevant Diseases

Multiple Sclerosis

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

MBP

Full Name

Myelin Basic Protein

Gene ID

4135

Uniprot ID

P02688

Target Overview

Myelin Basic Protein (MBP) is a major structural protein of the myelin sheath in the central nervous system. Its primary function is to ensure the proper compaction of the myelin layers by mediating the adhesion of the cytosolic surfaces of the oligodendrocyte membrane. This is essential for maintaining the integrity of the myelin sheath, which insulates nerve axons and facilitates rapid nerve impulse conduction. Due to its abundance and location, MBP is also a primary autoantigen in Multiple Sclerosis (MS), where an autoimmune attack against MBP and other myelin components leads to demyelination and neurodegeneration.

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