NoGeneST™ Anti-Tau Aptamer, aTau aptamer

Name: NoGeneST™ Anti-Tau Aptamer, aTau aptamer
SKU: NRYF-0625-HZ87
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ87]

Aptamer designed to specifically recognize Microtubule-Associated Protein Tau, a central protein in the pathology of Alzheimer's disease and other tauopathies.

Target:: Tau

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Product Overview

Species

Human

Relevant Diseases

Alzheimer's Disease

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

Tau

Full Name

Microtubule-associated protein tau

Gene ID

4137

Uniprot ID

P10636

Target Overview

Microtubule-associated protein tau (Tau) is a protein primarily found in neurons that plays a crucial role in stabilizing microtubules within axons. These microtubules are essential components of the neuronal cytoskeleton, acting as tracks for intracellular transport. In a class of neurodegenerative disorders known as "tauopathies," which includes Alzheimer's disease, Tau protein undergoes abnormal hyperphosphorylation. This chemical change causes it to detach from microtubules and aggregate into insoluble, paired helical filaments. These filaments accumulate inside neurons to form neurofibrillary tangles (NFTs), which are a primary pathological hallmark of these diseases.

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