NoGeneST™ SOD1-ASO, Antisense Oligonucleotide

Name: NoGeneST™ SOD1-ASO, Antisense Oligonucleotide
SKU: NRYF-0625-XY19
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-XY19]

Target:: SOD1

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Product Overview

Description

SOD1-ASO is an antisense oligonucleotide modified with a phosphorothioate (PS) backbone + 2'-MOE (2'-O-methoxyethyl) that targets SOD1 mRNA and reduces the production of mutant SOD1 protein through ASO-mediated degradation, thereby delaying disease progression.

Species

Human

Applications

Our SOD1-ASO specifically targets Superoxide Dismutase 1 (SOD1), a gene associated with Amyotrophic Lateral Sclerosis (ALS). By reducing SOD1 expression, it helps researchers study the role of SOD1 in oxidative stress, neuronal apoptosis, and neurodegeneration, facilitating the discovery of effective treatments for ALS.

Relevant Diseases

Amyotrophic lateral sclerosis

Properties

Appearance

Solid

Shipping

Room temperature

Storage

Store at -20°C, sealed and away from moisture.
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).