Creative Biolabs

Rat Anti-MBP Monoclonal Antibody (W0010), Unconjugated

[CAT#: NAB2007FY254]

Rat Monoclonal [W0010] to MBP

Host Species:
Rat
Species Reactivity:
Bovine; Human
Applications:
ELISA; IF; IHC-Fr

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Description
The rat anti-MBP antibody recognizes myelin basic protein (MBP), a component of myelin that is thought to play a role in the formation of nerve myelin in the central nervous system.
Immunogen
Bovine myelin basic protein.
Species Reactivity
Bovine; Human
Clonality
Monoclonal
Host Species
Rat
Isotype
IgG2b
Clone Number
W0010
Applications
ELISA; IF; IHC-Fr
Relevant Diseases
Neurological Disorders
Research Areas
Growth and Development
Conjugation
Unconjugated
Form
Tissue Culture Supernatant-liquid
Formulation
Tissue Culture Supernatant-liquid
0.09% Sodium Azide
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend micr°Centrifugation before use.
Target
Myelin Basic Protein
Official Name
MBP
Full Name
Myelin basic protein
Alternative Names
MBP; entrez:4155; myelin basic protein; Myelin basic protein; Myelin_BP; IPR000548
Gene ID
4155(Human); 17196(Mouse); 24547(Rat)
Uniprot ID
P02686(Human); P04370(Mouse); P02688(Rat)
1. Glynn, P. et al. (1987) Basic protein dissociating from myelin membranes at physiological ionic strength and pH is cleaved into three major fragments.
2. Groome, N. et al. (1988) New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.
3. Matsuo, A. et al. (1997) Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.
4. Jackson, S.J. et al. (2004) Cannabinoid-mediated neuroprotection following interferon-gamma treatment in a three-dimensional mouse brain aggregate cell culture.
5. Friess, M. et al. (2016) Intracellular ion signaling influences myelin basic protein synthesis in oligodendrocyte precursor cells.
Neural Genes
Neural Antibodies
Neural Proteins & Peptides
For Research Use Only. Not For Clinical Use.
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