iNeu™ Glutamatergic Neurons TDP-43 M337V/M337V, ALS Model
Human iPSC-derived ALS and FTD disease model
- Species:
- Human
- Cell Types:
- Glutamatergic Neurons
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Description
Relevant disease model cells have homozygous TDP-43 M337V/M337V mutations, and both can be used with their genetically matched controls.
Features
Disease model cells were paired with genetically matched wild-type glutamatergic neurons to study the effects of mutant TDP-43 proteins on disease progression.
Scalable
Available in industrial-scale quantities, with industry-leading seeding densities, and at an affordable price, cells can be used from research to high-throughput screening.
Fast
Disease model cells and isogenic controls were ready for experiments as early as 2 days after resuscitation and formed structural neuronal networks by 11 days.
Neurological Disease Models
Cell Types
Application Notes
Drug discovery and development
Disease modelling
High-throughput screening
Electrophysiological assays (MEA)
Co-culture studies
Mutation Description
Relevant Diseases
Species
Size
Form
Cell State
Growth Pattern
Seeding Density
Tissue Source
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Additional Donor Information
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