Human iPS Cell Line (Alzheimer's Disease)

[CAT#: NCL-2105-P121-IX]

These cells can be used for disease modeling, drug screening and toxicology testing.

Species:: Human

Applications:: In Vivo Like Assay

Cell Types:: iPSC

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Product Overview

Description

Human iPS Cell Line (Alzheimer's Disease) from Creative Biolabs are isolated from Human iPS Cells derived from dermal fibroblasts of a Alzheimer's Disease patient. The patient was diagnosed with TYPE 4 AD with a heterozygous N141I mutation in PSEN2 gene. They are cryopreserved after purification and delivered frozen.

Neurological Disease Models

AD-related Cells

Cell Types

iPSC

Applications

In Vivo Like Assay

Application Notes

Media

Human iPSC Growth Medium (Cat # NCL-2105-P122-IX)

Human iPSC Feeder-Free Growth Medium (Cat # NCL-2105-P123-IX)

Human iPSC Xeno-Free Growth Medium (Cat#NCL-2105-P124-IX)

iMEF Feeder (CF1), irradiated (Cat # NCL-2105-P125-IX)

Relevant Diseases

Alzheimer's Disease

Species

Human

Properties

Size

Each vial contains>1 x 10e6 cells.

Freeze Medium

90% FBS+10% DMSO

Tissue Source

Human iPS Cells derived from dermal fibroblasts of a Alzheimer's Disease patient. The patient was diagnosed with TYPE 4 AD with a heterozygous N141I mutation in PSEN2 gene.

Cell Purity

>95%

Cell Viability

>90%

Mycoplasma Testing

Negative

Sterility Testing

The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Genetic Stability Testing

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

Shipping

Frozen on dry ice

Storage

Liquid nitrogen

Handling Advice

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.