Mouse Anti-SNCA Monoclonal Antibody (CBP2765)

Product Overview

Description

Aggregated and hyper-phosphorylated forms of α-syn protein are the pathological hallmark of Lewy body disease, which includes Parkinson's disease (PD), diffuse Lewy body disease (DLBD), and Lewy body variant of Alzheimer's disease (LBV). This antibody can recognize all the isoforms of α-syn.

Expression Host

Mammalian cells

Immunogen

Alpha Synuclein fusion protein Ag1285

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP2765

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

GPCR

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Alpha Synuclein

Official Name

SNCA

Full Name

Synuclein, alpha (non A4 component of amyloid precursor)

Alternative Names

Alpha synuclein; a-Synuclein; NACP; PARK1; PARK4; PD1; SNCA

Gene ID

6622(Human)

Uniprot ID

P37840(Human)

References

1. Liu, W., Fu, R., Wang, Z., Liu, S., Tang, C., Li, L., & Yin, D. (2020). Regular Aerobic Exercise-Alleviated Dysregulation of CAMKIIα Carbonylation to Mitigate Parkinsonism via Homeostasis of Apoptosis With Autophagy. Journal of Neuropathology & Experimental Neurology, 79(1), 46-61.

Publications